Trial and error: should pregnant women be research subjects?

Trial and error: should pregnant women be research subjects?

A single dose of 200 mg/kg razoxane protected mice against the sub-chronic lethal effects (i.e. within 21 days) of 10 mg/kg daunomycin. When the razoxane dose was split into 2 doses of 100 mg/kg, even better protection against higher doses of daunomycin was obtained. The best protective effect was seen when the razoxane was given 24 h before or simultaneously with the daunomycin, and it was sti...

Should all pregnant women be screened for hypothyroidism?

Should pregnant women be excluded from a community-based lifestyle intervention trial? A case study

Kerala, the southernmost Indian state, is known as the diabetes capital of the country. A community-based lifestyle modification program was implemented in the rural areas of Kerala, India, to assess effectiveness in reducing the incidence of type 2 diabetes mellitus (T2DM) among individuals at high risk. High-risk individuals for T2DM were identified through home screening and enrolled into th...

Should pregnant women be screened for drugs of abuse?

SirWe would like to compliment Drs Bosio et al for the first reported prospective screening study for drug abuse in an Irish obstetric population. We would disagree, however, with the deduction that "drug abuse is not a serious problem among Dublin's pregnant population." 43 cases of neonatal drug withdrawal were identified at our hospital between July 1996 and June 1997 and these babies had si...

I-14: Assisted Reproduction and Religion What Consideration Should Be and Should Not Be Relevant,

Several important issues are pertinent to an ethical discussion of the new technology today grouped under the name Assisted Reproduction Technology (ART). This is a moral imperative because each of us must decide what is to be considered ethically acceptable in assisted reproduction. Reflecting on the ethical dimension of ‘creating’ a new human life can play a major role in ensuring that in eac...